Antiemetics: Mechanisms and Clinical Use

Antiemetics

Antiemetics are the drugs used to suppress nausea and vomiting. They act on various receptors and pathways, depending on the cause of the symptoms. A deep understanding of antiemetics is essential in clinical practice, particularly in oncology, gastroenterology, anesthesia, and primary care. Nausea and vomiting are complex reflexes coordinated by brainstem centers (the vomiting center … Read more

5-HT₃ Receptor Antagonists: Mechanism, Clinical Uses, and Side Effects

5-HT₃ Receptor Antagonists

Nausea and vomiting unpleasant as they are can  sometimes occur due to significant clinical problems. Constant Vomiting can lead to severe dehydration, electrolyte imbalance, and a decreased quality of life especially in patients undergoing cancer treatments like chemotherapy, radiotherapy, or surgery. Over the last few decades, the discovery and use of 5-HT₃ receptor antagonists has … Read more