Antiemetics are the drugs used to suppress nausea and vomiting. They act on various receptors and pathways, depending on the cause of the symptoms. A deep understanding of antiemetics is essential in clinical practice, particularly in oncology, gastroenterology, anesthesia, and primary care. Nausea and vomiting are complex reflexes coordinated by brainstem centers (the vomiting center … Read more
Nausea and vomiting unpleasant as they are can sometimes occur due to significant clinical problems. Constant Vomiting can lead to severe dehydration, electrolyte imbalance, and a decreased quality of life especially in patients undergoing cancer treatments like chemotherapy, radiotherapy, or surgery. Over the last few decades, the discovery and use of 5-HT₃ receptor antagonists has … Read more
In pharmacology and clinical medicine, 5-alpha-reductase inhibitors (5-ARIs) have a variety of life saving uses. These drugs have been widely used to manage conditions such as benign prostatic hyperplasia (BPH) and male pattern baldness (androgenetic alopecia) which are linked to the androgen hormone dihydrotestosterone (DHT). What is 5-Alpha-Reductase? To understand these drugs, we first need … Read more